Structural basis for origin recognition complex 1 protein-silence information regulator 1 protein interaction in epigenetic silencing
نویسندگان
چکیده
منابع مشابه
Structural basis for origin recognition complex 1 protein-silence information regulator 1 protein interaction in epigenetic silencing.
The interaction between silence information regulator 1 protein (Sir1p) and origin recognition complex 1 protein (Orc1p), the largest subunit of the origin recognition complex, plays an important role in the establishment of transcriptional silencing at the cryptic mating-type gene loci in Saccharomyces cerevisiae. Sir1p binds the N-terminal region of Orc1p encompassing a Bromo-adjacent homolog...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2005
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0502946102